ERA-NET NEURON : TRANSNATIONAL RESEARCH PROJECTS ON MENTAL DISORDERS

Array ( [0] => Array ( [value] => Recherche [safe] => Recherche [view] => Recherche ) )
Domaine de recherche :
Santé
Type de financement :
ERA-Net / JTI / JPI
Type d'instrument :
N / A
Code de l'appel : ERA-NET NEURON
En savoir plus
À noter :

Aim of the call

The aim of the call is to facilitate multinational, collaborative research projects that will address important questions related to mental health and mental disorders. These may include research on mood disorders (major depression, bipolar disorders), anxiety disorders, psychotic disorders, autism spectrum disorders, substance use disorders, and other mental disorders. Research questions may encompass the entire life span. Since many mental disorders develop during childhood, adolescence and early adulthood (< 25 years), it is a clear interest for society to find pharmacological, psychological therapies and brain stimulation therapies, besides new diagnostic strategies, to promote mental health in this focus group. Research on dementia is excluded from the present call. The call will accept novel and original research proposals within the breadth of research understanding basic mechanisms of disease to proof-of-concept clinical studies in humans.

The NEURON funding organizations particularly wish to promote multi-disciplinary work and translational research proposals that combine basic and clinical approaches. For many research questions, collaboration within a consortium of psychiatrists and neurologists is important and therefore encouraged, where appropriate, along with fundamental neuroscientists, and disciplines with specific expertise such as e.g. neuro-pediatricians.

Research proposals should cover at least one of the following areas:

a) Fundamental research on the pathogenesis, aetiology and resilience mechanisms of mental disorders. This may include the development of innovative or shared resources and technologies. The relevance of the research to disease must be clearly indicated.

b) Clinical research to develop novel strategies for prevention, (early) diagnosis, patient stratification, therapy, and/or rehabilitation procedures for mental disorders.

 

Proposals may include, among others, immuno-psychiatric approaches, studies on (epi) genetic causes of mental disorders, studies on social, environmental and biological risk and resilience factors. Innovative treatment approaches may include e.g. brain stimulation, use of mobile health applications, and combinations of cognitive and physical or psychosocial and pharmacological interventions.

The individual components of joint applications should be complementary and contain novel, ambitious ideas. There should be clear added value in funding the collaboration over the individual projects.

Clinical studies are eligible up to the point of proofof concept. Exploitation of existing clinical data sets is encouraged. Appropriate access to relevant, well-characterized patient populations or suitable biomaterial collections must be demonstrated.  Pooling and synergistic usage of existing data, patient cohorts, and biomaterial or animal model collections are expected. Applicants should also demonstrate that they have the expertise and range of skills required to conduct the study or that appropriate  collaborations  are  in  place. Animal  models or  cell  models used  in  the  project  should already be established and validated. The development of new animal or cell models is excluded from the scope of the call unless it is a marginal part of the proposal (i.e. as a strategy to strengthen the results or hypothesis in a project).

Research consortia are encouraged to meaningfully involve patients and carers. Applicants are expected to make every effort to include patient approaches, where appropriate, at each stage of the research process and/or specify plans for future involvement.